Dilaudid Tablets

Pronunciation: HYE-droe-MOR-fone
Generic Name: Hydromorphone
Brand Name: Dilaudid

Dilaudid is used for:

Treating pain in certain patients.

Dilaudid is an opioid (narcotic) analgesic. It works by binding to certain receptors in the brain and nervous system to reduce pain.

Do NOT use Dilaudid if:

• you are allergic to any ingredient in Dilaudid or any other codeine- or morphine-related medicine (eg, morphine, codeine, oxycodone)


• you have difficult or slowed breathing, chronic obstructive pulmonary disease (COPD), or right-sided heart problems (cor pulmonale), or you are having a severe asthma attack


• you are in labor


• you have severe diarrhea or other bowel problems caused by antibiotics or poisoning


• you have a brain injury or growths in the brain along with increased pressure in the brain


• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dilaudid:

Some medical conditions may interact with Dilaudid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of lung or breathing problems (eg, asthma, emphysema, bronchitis), seizures (eg, epilepsy), adrenal gland problems, an enlarged prostate, heart problems, low blood pressure, dehydration, low blood volume, an underactive thyroid, or urinary blockage


• if you have severe drowsiness, a recent head injury, spinal problems, growths in the brain, or increased pressure in the brain


• if you have liver or kidney problems, gallbladder problems, or stomach or bowel problems (eg, inflammation), or if you have had recent stomach or bowel surgery


• if you drink alcohol regularly, have symptoms of alcohol withdrawal, or have a history of suicidal thoughts or attempts


• if you have a personal or family history of mental or mood problems, alcohol abuse, or other substance abuse or dependence


• if you are in poor health or shock, or will be having surgery

Some MEDICINES MAY INTERACT with Dilaudid. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Phenothiazines (eg, chlorpromazine) because the risk of low blood pressure may be increased


• Barbiturate anesthetics (eg, thiopental), cimetidine, or sodium oxybate (GHB) because the risk of severe drowsiness, coma, or slowed or difficult breathing may be increased


• Agonist/antagonist analgesics (eg, pentazocine) or naltrexone because they may decrease Dilaudid's effectiveness and withdrawal may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dilaudid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dilaudid:

Use Dilaudid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Dilaudid may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Dilaudid must only be taken by mouth.


• If you are taking Dilaudid for persistent pain, take it on a regular schedule to help control the pain more effectively.


• Do not change your dose or suddenly stop taking Dilaudid without checking with your doctor.


• If Dilaudid is no longer needed, dispose of it as soon as possible. Ask your doctor or pharmacist how to dispose of Dilaudid properly.


• If you miss a dose of Dilaudid and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dilaudid.

Important safety information:

• Dilaudid may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol, other opiate pain medicines, or certain other medicines. Use Dilaudid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you take Dilaudid; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Dilaudid may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.


• Dilaudid may be habit-forming. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. Misuse or abuse of Dilaudid may cause severe side effects, including severe breathing problems, seizures, coma, and possibly death.


• Some of these products contain sulfites. Sulfites may cause an allergic reaction in some patients (eg, asthma patients). If you have ever had an allergic reaction to sulfites, ask your pharmacist if this product has sulfites in it.


• Constipation is a common side effect of Dilaudid. Talk to your doctor about using laxatives or stool softeners to prevent or treat constipation while you use Dilaudid.


• If your pain continues or becomes worse or if you have side effects that concern you, contact your doctor.


• Tell your doctor or dentist that you take Dilaudid before you receive any medical or dental care, emergency care, or surgery.


• Use Dilaudid with caution in the ELDERLY; they may be more sensitive to its effects, especially drowsiness and breathing problems.


• Dilaudid should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Dilaudid may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Dilaudid while you are pregnant. Dilaudid is found in breast milk. Do not breast-feed while taking Dilaudid.

When used for long periods of time or at high doses, Dilaudid may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Dilaudid stops working well. Do not take more than prescribed.

Some people who use Dilaudid for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. Dependence is unlikely to be an issue in terminally ill patients where comfort is more important. If you are taking Dilaudid regularly, do not suddenly stop taking it without checking with your doctor. WITHDRAWAL symptoms have occurred when Dilaudid is suddenly stopped and may include anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea and vomiting; pain; rigid muscles; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping. Contact your doctor if you notice any of these symptoms after stopping Dilaudid.

Possible side effects of Dilaudid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness, drowsiness; dry mouth; flushing; lightheadedness; nausea; sweating; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fainting; fast, slow, or irregular heartbeat; hallucinations; mental or mood changes; seizure; severe or persistent dizziness or drowsiness; severe or persistent headache or vomiting; shallow, slowed, or difficult breathing; tremor; trouble urinating; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Dilaudid side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include bluish skin; chest pain; cold and clammy skin; coma; difficult or slow breathing; excessive sweating; limp muscles; nausea and vomiting; numbness of an arm or leg; pinpoint pupils; seizures; severe drowsiness or dizziness; slow or irregular heartbeat.

Proper storage of Dilaudid:

Store Dilaudid at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store Dilaudid in the bathroom. Keep Dilaudid out of the reach of children and away from pets.

General information:

• If you have any questions about Dilaudid, please talk with your doctor, pharmacist, or other health care provider.


• Dilaudid is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Dilaudid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Dilaudid resources

• Dilaudid Side Effects (in more detail)
• Dilaudid Use in Pregnancy & Breastfeeding
• Drug Images
• Dilaudid Drug Interactions
• Dilaudid Support Group
• 136 Reviews for Dilaudid - Add your own review/rating

Compare Dilaudid with other medications

• Cough
• Pain

Pletal

Pronunciation: sye-LOE-sta-zol
Generic Name: Cilostazol
Brand Name: Pletal

Medicines similar to Pletal have shortened the lives of people with certain types of heart failure. Do not use Pletal if you have any type of heart failure.

Pletal is used for:

Reducing symptoms of intermittent claudication (pain, cramping, numbness, or weakness in the legs) that may occur with walking. It may also be used for other conditions as determined by your doctor.

Pletal is a phosphodiesterase type 3 inhibitor. Pletal works by widening blood vessels to increase blood flow. It also decreases the ability of platelets to stick together and form clots.

Do NOT use Pletal if:

• you are allergic to any ingredient in Pletal


• you have heart failure, bleeding problems or a disorder that causes the inability to form blood clots, or active bleeding (eg, bleeding peptic ulcer, bleeding in the brain)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Pletal:

Some medical conditions may interact with Pletal. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have liver or kidney problems, or low blood platelet levels


• if you have recently had surgery or any type of bleeding

Some MEDICINES MAY INTERACT with Pletal. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Antiplatelet medicines (eg, clopidogrel) because the risk of bleeding may be increased


• Certain azole antifungals (eg, ketoconazole), diltiazem, esomeprazole, certain macrolide antibiotics (eg, erythromycin), nefazodone, omeprazole, protease inhibitors (eg, boceprevir, ritonavir), certain selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine, fluvoxamine, sertraline), or telithromycin because they may increase the risk of Pletal's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Pletal may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Pletal:

Use Pletal as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Pletal. Talk to your pharmacist if you have questions about this information.


• Take Pletal by mouth at least 30 minutes before or 2 hours after eating.


• Check with your doctor before you eat grapefruit or drink grapefruit juice while you take Pletal.


• The effects of Pletal are not immediate. Although you may experience the benefits of Pletal 2 to 4 weeks after beginning treatment, treatment for up to 12 weeks may be necessary before Pletal takes effect. Do not stop taking Pletal or change your dose without checking with your doctor.


• Pletal works best if it is taken at the same time(s) each day.


• If you miss a dose of Pletal, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If more than 1 dose is missed, contact your health care provider or pharmacist.

Ask your health care provider any questions you may have about how to use Pletal.

Important safety information:

• Pletal may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Pletal with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Pletal may rarely reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.


• Pletal may rarely lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.


• Tell your doctor or dentist that you take Pletal before you receive any medical or dental care, emergency care, or surgery.


• Lab tests, including complete blood cell counts, may be performed while you take Pletal. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Pletal should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY AND BREAST-FEEDING: If you are pregnant or become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Pletal while you are pregnant. It is not known if Pletal is found in breast milk. Do not breast-feed while you are taking Pletal.

Possible side effects of Pletal:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal stools; back pain; diarrhea; dizziness; gas; headache; increased cough; indigestion; light-headedness; mild sore throat; muscle aches; nausea; runny nose; stomach pain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; chest, jaw, or left arm pain; confusion; fainting; fast or irregular heartbeat; fever, chills, or persistent cough or sore throat; numbness of an arm or leg; one-sided weakness; red, swollen, blistered, or peeling skin; severe or persistent dizziness or light-headedness; shortness of breath; slurred speech; sudden, severe headache or vomiting; sudden, unusual weight gain; swelling of the hands, ankles, or feet; unusual bruising or bleeding; vision changes (eg, blindness, double vision); vomiting material that looks like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Pletal side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include diarrhea; fainting; fast or irregular heartbeat; severe headache, dizziness, or light-headedness.

Proper storage of Pletal:

Store Pletal between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pletal out of the reach of children and away from pets.

General information:

• If you have any questions about Pletal, please talk with your doctor, pharmacist, or other health care provider.


• Pletal is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Pletal. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Pletal resources

• Pletal Side Effects (in more detail)
• Pletal Use in Pregnancy & Breastfeeding
• Drug Images
• Pletal Drug Interactions
• Pletal Support Group
• 1 Review for Pletal - Add your own review/rating

• Pletal Prescribing Information (FDA)


• Pletal Advanced Consumer (Micromedex) - Includes Dosage Information


• Pletal Concise Consumer Information (Cerner Multum)


• Pletal Monograph (AHFS DI)


• Cilostazol Prescribing Information (FDA)


• Cilostazol Professional Patient Advice (Wolters Kluwer)

Compare Pletal with other medications

• Intermittent Claudication

Curadon

Curadon may be available in the countries listed below.

Ingredient matches for Curadon

Paracetamol

Paracetamol is reported as an ingredient of Curadon in the following countries:

• Sweden

International Drug Name Search

Cresadex

Cresadex may be available in the countries listed below.

Ingredient matches for Cresadex

Rosuvastatin

Rosuvastatin is reported as an ingredient of Cresadex in the following countries:

• Peru

Rosuvastatin calcium salt (a derivative of Rosuvastatin) is reported as an ingredient of Cresadex in the following countries:

• Chile

International Drug Name Search

Dilaudid-HP

Generic Name: hydromorphone (Injection route)

hye-droe-MOR-fone hye-droe-KLOR-ide

Injection route(Solution;Powder for Solution)

Hydromorphone is a potent Schedule II opioid agonist which has the highest potential for abuse and risk of producing respiratory depression. Alcohol, other opioids and central nervous system depressants (sedative-hypnotics) potentiate the respiratory depressant effects of hydromorphone, increasing the risk of respiratory depression that might result in death. Dilaudid-HP(R) is a highly concentrated solution of hydromorphone intended for use in opioid-tolerant patients. Do not confuse Dilaudid-HP(R) with standard parenteral formulations of hydromorphone or other opioids as overdose and death could result .

Commonly used brand name(s)

In the U.S.

• Dilaudid


• Dilaudid-HP

Available Dosage Forms:

• Solution


• Powder for Solution

Therapeutic Class: Analgesic

Chemical Class: Hydromorphone

Uses For Dilaudid-HP

Hydromorphone belongs to the group of medicines called narcotic analgesics, which are medicines used to relieve pain. Dilaudid® is used to relieve pain in patients who require a narcotic pain medication. Dilaudid-HP® is used to relieve moderate-to-severe pain in patients who are opioid-tolerant and who require higher doses of opioid medicine.

Hydromorphone acts on the central nervous system (CNS) to relieve pain. Some of the side effects are also caused by actions in the CNS. When hydromorphone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

This medicine is available only with your doctor's prescription.

Before Using Dilaudid-HP

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of hydromorphone injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hydromorphone injection in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving hydromorphone injection.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Naltrexone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Adinazolam


• Alfentanil


• Alprazolam


• Amobarbital


• Anileridine


• Aprobarbital


• Aripiprazole


• Brofaromine


• Bromazepam


• Brotizolam


• Buprenorphine


• Buspirone


• Butabarbital


• Butalbital


• Butorphanol


• Carisoprodol


• Chloral Hydrate


• Chlordiazepoxide


• Chlorpromazine


• Chlorzoxazone


• Clobazam


• Clonazepam


• Clorazepate


• Clorgyline


• Clozapine


• Codeine


• Dantrolene


• Desflurane


• Dexmedetomidine


• Dezocine


• Diazepam


• Diphenhydramine


• Doxylamine


• Enflurane


• Estazolam


• Eszopiclone


• Ethchlorvynol


• Fentanyl


• Flumazenil


• Flunitrazepam


• Fluphenazine


• Flurazepam


• Fospropofol


• Furazolidone


• Halazepam


• Haloperidol


• Halothane


• Hydrocodone


• Hydromorphone


• Hydroxyzine


• Iproniazid


• Isocarboxazid


• Isoflurane


• Ketamine


• Ketazolam


• Lazabemide


• Levorphanol


• Linezolid


• Lorazepam


• Lormetazepam


• Loxapine


• Medazepam


• Meperidine


• Mephenesin


• Mephobarbital


• Meprobamate


• Mesoridazine


• Metaxalone


• Methocarbamol


• Methohexital


• Midazolam


• Moclobemide


• Molindone


• Morphine


• Morphine Sulfate Liposome


• Nalbuphine


• Nialamide


• Nitrazepam


• Nitrous Oxide


• Nordazepam


• Olanzapine


• Opium


• Oxazepam


• Oxycodone


• Oxymorphone


• Paliperidone


• Pargyline


• Pentazocine


• Pentobarbital


• Perphenazine


• Phenelzine


• Phenobarbital


• Pimozide


• Prazepam


• Procarbazine


• Promazine


• Promethazine


• Propofol


• Propoxyphene


• Quazepam


• Quetiapine


• Ramelteon


• Rasagiline


• Remifentanil


• Risperidone


• Secobarbital


• Selegiline


• Sevoflurane


• Sodium Oxybate


• Sufentanil


• Tapentadol


• Temazepam


• Thiopental


• Thioridazine


• Thiothixene


• Toloxatone


• Tranylcypromine


• Triazolam


• Trifluoperazine


• Zaleplon


• Ziprasidone


• Zolpidem

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Addison's disease (adrenal gland problem) or


• Alcohol abuse, acute or


• Asthma, severe, history of or


• Breathing problems, severe (e.g., hypercapnia, hypoxia) or


• Chronic obstructive pulmonary disease (COPD) or


• Cor pulmonale (serious heart condition) or


• Drug dependence, especially narcotic abuse or dependence, or history of or


• Enlarged prostate (BPH, prostatic hypertrophy) or


• Gallbladder disease or gallstones or


• Head injuries or


• Hypothyroidism (an underactive thyroid) or


• Kyphoscoliosis (curvature of the spine with breathing problems) or


• Mental illness, history of or


• Problems with passing urine—Use with caution. May increase risk for more serious side effects.

• Allergy to medicines containing sulfites or


• Asthma, acute or severe or


• Bowel blockage or


• Paralytic ileus (bowels stop working and may be blocked) or


• Respiratory depression (very slow breathing)—Dilaudid® and Dilaudid-HP® should not be used in patients with these conditions.

• Hypotension (low blood pressure) or


• Pancreatitis (inflammation of the pancreas) or


• Seizures, history of—Use with caution. May make these conditions worse.

• Kidney disease or


• Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of hydromorphone

This section provides information on the proper use of a number of products that contain hydromorphone. It may not be specific to Dilaudid-HP. Please read with care.

Dilaudid-HP® injection should only be used by patients who have already been taking narcotic pain medicines, also called opioids. These patients are called opioid-tolerant. If you are uncertain whether or not you are opioid-tolerant, check with your doctor before using this medicine.

A nurse or other trained health professional will give you this medicine in a hospital. This medicine may be given as a shot under the skin, as a shot into one of your muscles, or through a needle placed in one of your veins.

Hydromorphone injection may sometimes be given at home to patients who do not need to be in the hospital. If you are using this medicine at home, your doctor will teach you how to prepare and inject the medicine. Be sure that you understand exactly how the medicine is prepared and injected.

You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.

Use a new needle and syringe each time you inject your medicine.

If the medicine in the vial or ampule has changed color, or if you see particles in it, do not use it.

Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For injection (intramuscular or subcutaneous) dosage forms:
  
  • For moderate to severe pain:
    
    • For patients who are not taking opioid medicines (not opioid-tolerant):
      
      • Adults—At first, 1 to 2 milligrams (mg) injected under your skin or into one of your muscles every 2 to 3 hours as needed. Your doctor may adjust your dose as needed and tolerated.
      
      
      • Children—Use and dose must be determined by your doctor.
      
      
    
    
    • For patients who are already taking opioid medicines (opioid-tolerant):
      
      • Adults—Your dose is the same as your dose of Dilaudid® or your doctor will determine your dose based on the narcotic pain medicine you are already receiving.
      
      
      • Children—Use and dose must be determined by your doctor.
      
      
    
    
  
  

Missed Dose

Call your doctor or pharmacist for instructions.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

If you store this medicine at home, keep it at room temperature, away from heat and direct light.

Flush all leftover medicine down the toilet after you have finished your treatment. Also, flush old medicine after the expiration date has passed. This medicine is one of only a few medicines that should be disposed of this way.

Precautions While Using Dilaudid-HP

It is very important that your doctor check your progress while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert) and may cause serious side effects. Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers, or sleeping medicine; other prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before drinking alcohol or taking any of the medicines listed above while you are using this medicine.

This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.

Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.

This medicine may make you dizzy, drowsy, confused, or disoriented. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are receiving this medicine.

If you have been using this medicine regularly for several weeks or longer, do not suddenly stop using it without checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble with sleeping.

Some babies who are born to mothers physically dependent on this medicine will also be physically dependent and may have breathing problems and withdrawal symptoms. This could be life-threatening and requires immediate medical attention. Check with your doctor right away if your child has the following withdrawal symptoms: difficulty with breathing, shortness of breath, excessive crying, irritability, fever, vomiting, or tremors.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Dilaudid-HP Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

• Abdominal or stomach pain


• blurred vision


• change in the ability to see colors, especially blue or yellow


• chest pain or discomfort


• cold, clammy skin


• confusion


• cough


• difficult or troubled breathing


• dizziness


• fast, pounding, or irregular heartbeat or pulse


• fast or weak pulse


• headache


• irregular, fast, slow, or shallow breathing


• lightheadedness, dizziness, or fainting


• loss of appetite


• low blood pressure


• noisy breathing


• pale or blue lips, fingernails, or skin


• severe constipation


• severe vomiting


• shortness of breath


• sleeplessness


• slow or irregular heartbeat


• sweating


• tightness in the chest


• trouble with sleeping


• unable to sleep


• unconscious


• unusual tiredness


• very slow breathing


• very slow heartbeat or pulse


• vomiting


• wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Bigger, dilated, or enlarged pupils (black part of the eye)


• decreased awareness or responsiveness


• increased sensitivity of the eyes to light


• no muscle tone or movement


• sleepiness or unusual drowsiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Anxiety


• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings


• bad, unusual, or unpleasant (after) taste


• change in taste


• chills


• constricted, pinpoint, or small pupils (black part of the eye)


• decrease in the frequency of urination


• decrease in urine volume


• diarrhea


• difficulty having a bowel movement (stool)


• difficulty in passing urine (dribbling)


• double vision


• dry mouth


• false or unusual sense of well-being


• feeling of warmth


• hives or welts


• hyperventilation


• irritability


• loss of appetite


• muscle stiffness or tightness


• nausea


• painful urination


• redness, pain, or swelling at the injection site


• redness of the face, neck, arms, and occasionally, upper chest


• relaxed and calm


• seeing, hearing, or feeling things that are not there


• seeing double


• shaking


• skin itching


• sleepiness


• uncontrolled eye movements


• upper abdominal or stomach pain


• weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Dilaudid-HP side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Dilaudid-HP resources

• Dilaudid-HP Side Effects (in more detail)
• Dilaudid-HP Use in Pregnancy & Breastfeeding
• Dilaudid-HP Drug Interactions
• Dilaudid-HP Support Group
• 1 Review for Dilaudid-HP - Add your own review/rating

• Dilaudid-HP MedFacts Consumer Leaflet (Wolters Kluwer)


• Dilaudid-HP Prescribing Information (FDA)


• Dilaudid Prescribing Information (FDA)


• Dilaudid Consumer Overview


• Dilaudid MedFacts Consumer Leaflet (Wolters Kluwer)


• Exalgo Prescribing Information (FDA)


• Exalgo Consumer Overview


• Exalgo MedFacts Consumer Leaflet (Wolters Kluwer)


• Hydromorphone Prescribing Information (FDA)


• Hydromorphone Hydrochloride Monograph (AHFS DI)


• Palladone Prescribing Information (FDA)


• Palladone Extended-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Dilaudid-HP with other medications

• Anesthetic Adjunct
• Pain

Epeso

Epeso may be available in the countries listed below.

Ingredient matches for Epeso

Eperisone

Eperisone hydrochloride (a derivative of Eperisone) is reported as an ingredient of Epeso in the following countries:

• Japan

International Drug Name Search

Dilacor XR

Generic Name: diltiazem (Oral route)

dil-TYE-a-zem

Commonly used brand name(s)

In the U.S.

• Cardizem


• Cardizem CD


• Cardizem LA


• Cartia XT


• Dilacor XR


• Dilt-CD


• Diltia XT


• Dilt-XR


• Diltzac


• Matzim LA


• Taztia XT


• Tiazac

Available Dosage Forms:

• Capsule, Extended Release


• Tablet, Extended Release


• Tablet


• Capsule, Extended Release, 24 HR


• Capsule, Extended Release, 12 HR

Therapeutic Class: Cardiovascular Agent

Pharmacologic Class: Calcium Channel Blocker

Chemical Class: Benzothiazepine

Uses For Dilacor XR

Diltiazem is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled .

Diltiazem is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, diltiazem relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload .

This medicine is available only with your doctor's prescription .

Before Using Dilacor XR

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of diltiazem in the pediatric population. Safety and efficacy have not been established .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of diltiazem in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require an adjustment in the dose for patients receiving diltiazem .

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Cisapride

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acebutolol


• Alprenolol


• Amiodarone


• Aprepitant


• Atazanavir


• Atenolol


• Atorvastatin


• Betaxolol


• Bevantolol


• Bisoprolol


• Bucindolol


• Carteolol


• Carvedilol


• Celiprolol


• Clonidine


• Clozapine


• Colchicine


• Crizotinib


• Dantrolene


• Dilevalol


• Dronedarone


• Droperidol


• Erythromycin


• Esmolol


• Everolimus


• Fentanyl


• Labetalol


• Levobunolol


• Lurasidone


• Mepindolol


• Metipranolol


• Metoprolol


• Nadolol


• Nebivolol


• Oxprenolol


• Penbutolol


• Pindolol


• Propranolol


• Ranolazine


• Simvastatin


• Sotalol


• Talinolol


• Tertatolol


• Timolol


• Tolvaptan

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Alfentanil


• Alfuzosin


• Amlodipine


• Aspirin


• Buspirone


• Carbamazepine


• Celecoxib


• Cilostazol


• Cimetidine


• Clopidogrel


• Colestipol


• Cyclosporine


• Dalfopristin


• Digitoxin


• Digoxin


• Dutasteride


• Efavirenz


• Enflurane


• Fosaprepitant


• Fosphenytoin


• Guggul


• Indinavir


• Lithium


• Lovastatin


• Methylprednisolone


• Midazolam


• Moricizine


• Nevirapine


• Nifedipine


• Phenytoin


• Quinupristin


• Rifampin


• Rifapentine


• Ritonavir


• Sirolimus


• St John's Wort


• Tacrolimus


• Triazolam

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Bowel blockage, severe or


• Congestive heart failure—Use with caution. May make this condition worse .

• Heart attack or


• Heart block (type of abnormal heart rhythm, can use if have a pacemaker that works properly) or


• Hypotension (low blood pressure), severe or


• Lung problem (e.g., pulmonary congestion) or


• Sick sinus syndrome (type of abnormal heart rhythm, can use if have a pacemaker that works properly)—Should not be used in patients with these conditions .

• Kidney disease or


• Liver disease—Use with caution. The effects of this medicine may be increased because of slower removal from the body .

Proper Use of diltiazem

This section provides information on the proper use of a number of products that contain diltiazem. It may not be specific to Dilacor XR. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet .

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well .

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease .

Swallow the extended-release tablet or extended-release capsule whole. Do not open, crush, or chew it. It is best to take the extended-release capsule on an empty stomach .

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For chest pain:
  
  • For oral dosage form (tablets):
    
    • Adults—At first, 30 milligrams (mg) four times a day before meals and at bedtime. Your doctor may increase your dose if needed.
    
    
    • Children—Use and dose must be determined by your doctor .
    
    
  
  
  • For oral dosage form (extended-release tablets):
    
    • Adults—At first, 180 mg once a day either in the evening or in the morning. Your doctor may increase your dose if needed.
    
    
    • Children—Use and dose must be determined by your doctor .
    
    
  
  
  • For oral dosage form (extended-release capsules):
    
    • Adults—At first, 120 mg once a day in the morning. Your doctor may increase your dose if needed.
    
    
    • Children—Use and dose must be determined by your doctor .
    
    
  
  

• For high blood pressure:
  
  • For oral dosage form (extended-release tablets):
    
    • Adults—At first, 180 to 240 milligrams (mg) once a day either in the morning or at bedtime. Your doctor may increase your dose if needed.
    
    
    • Children—Use and dose must be determined by your doctor .
    
    
  
  
  • For oral dosage form (extended-release capsules):
    
    • Adults—At first, 180 to 240 mg once a day in the morning. Your doctor may increase your dose if needed.
    
    
    • Children—Use and dose must be determined by your doctor .
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Dilacor XR

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects .

Low blood pressure (hypotension) may occur while taking this medicine. Check with your doctor right away if you have the following symptoms: blurred vision; confusion; severe dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly; sweating; or unusual tiredness or weakness .

Check with your doctor right away if you have pain or tenderness in the upper stomach; pale stools; dark urine; loss of appetite; nausea; unusual tiredness or weakness; or yellow eyes or skin. These could be symptoms of a serious liver problem .

Serious skin reactions can occur with this medicine. Check with your doctor right away if you have any of the following symptoms while taking this medicine: blistering, peeling, or loosening of the skin; chills; cough; diarrhea; itching; joint or muscle pain; red skin lesions, often with a purple center; skin rash; sore throat; sores, ulcers, or white spots in the mouth or on the lips; or unusual tiredness or weakness .

Dilacor XR Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Body aches or pain


• congestion


• cough


• dryness or soreness of throat


• fever


• hoarseness


• runny nose


• tender or swollen glands in neck


• trouble in swallowing


• voice changes

Less common

• Chest pain or discomfort


• chills


• diarrhea


• difficult or labored breathing


• feeling faint, dizzy, or lightheaded


• feeling of warmth or heat


• flushing or redness of skin, especially on face and neck


• general feeling of discomfort or illness


• headache


• joint pain


• loss of appetite


• muscle aches and pains


• nausea


• shivering


• shortness of breath


• slow or irregular heartbeat


• sore throat


• sweating


• swelling of hands, ankles, feet, or lower legs


• tightness in chest


• trouble sleeping


• unusual tiredness or weakness


• vomiting


• wheezing

Incidence not known

• Blistering, peeling, or loosening of skin


• itching


• large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• no heart beat


• red irritated eyes


• red skin lesions, often with a purple center


• sores, ulcers, or white spots in mouth or on lips

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Sneezing


• stuffy nose

Less common

• Acid or sour stomach


• belching


• constipation


• continuing ringing or buzzing or other unexplained noise in ears


• degenerative disease of the joint


• difficulty in moving


• hearing loss


• heartburn


• indigestion


• lack or loss of strength


• muscle aching or cramping


• muscle pains or stiffness


• pain or tenderness around eyes and cheekbones


• rash


• sleeplessness


• stomach discomfort, upset, or pain


• swollen joints


• unable to sleep

Incidence not known

• Hair loss or thinning of hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Dilacor XR side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Dilacor XR resources

• Dilacor XR Side Effects (in more detail)
• Dilacor XR Use in Pregnancy & Breastfeeding
• Drug Images
• Dilacor XR Drug Interactions
• Dilacor XR Support Group
• 0 Reviews for Dilacor XR - Add your own review/rating

• Dilacor XR Prescribing Information (FDA)


• Dilacor XR 24-Hour Sustained-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)


• Diltiazem Prescribing Information (FDA)


• Cardizem Consumer Overview


• Cardizem MedFacts Consumer Leaflet (Wolters Kluwer)


• Cardizem Prescribing Information (FDA)


• Cardizem CD Prescribing Information (FDA)


• Cardizem CD 24-Hour Sustained-Release Beads Capsules MedFacts Consumer Leaflet (Wolters Kluwer)


• Cardizem LA Prescribing Information (FDA)


• Cardizem LA 24-Hour Extended-Release Beads Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Cartia XT Prescribing Information (FDA)


• DILT-CD Prescribing Information (FDA)


• Dilt-XR Prescribing Information (FDA)


• Diltia XT Prescribing Information (FDA)


• Diltiazem Hydrochloride Monograph (AHFS DI)


• Matzim LA Prescribing Information (FDA)


• Taztia XT 24-Hour Extended-Release Beads Capsules MedFacts Consumer Leaflet (Wolters Kluwer)


• Taztia XT Prescribing Information (FDA)


• Tiazac Prescribing Information (FDA)


• Tiazac Consumer Overview

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